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您现在的位置: 医学全在线 > 考研院校 > 华东地区1 > 中国药科大学 > 院系导师 > 正文:中国药科大学医学考研药学院硕士研究生研究生导师资料:薛晓文
    

中国药科大学药学院硕士研究生导师简介:薛晓文

更新时间:2007/5/25 医学考研论坛 在线题库 评论
简历:薛晓文,博士,现任中国药科大学药物化学教研室副教授,主要从事有机化学以及药物化学领域的研究。1986年毕业于原南京药学院化学制药专业,留校任教。2000年赴美留学,2005年获美国迈阿密大学化学系有机化学专业博士学位。2005-2006年美国迈阿密大学化学系博士后。2006年9月回到中国药科大学工作。美国化学会会员。在

简历:薛晓文,博士,现任中国药科大学药物化学教研室副教授,主要从事有机化学以及药物化学领域的研究。1986年毕业于原南京药学院化学制药专业,留校任教。2000年赴美留学,2005年获美国迈阿密大学化学系有机化学专业博士学位。2005-2006年美国迈阿密大学化学系博士后。2006年9月回到中国药科大学工作。美国化学会会员。在化学领域的权威杂志美国化学会志(The Journal of American Chemical Society)以及有机化学杂志(The Journal of Organic Chemistry)等上发表了7篇SCI论文(其中6篇的影响因子在3.0 以上)。

  研究领域:抗肿瘤药物研究;非共价键弱作用力研究;不对称反应起源的研究等。

  主要论著
1. Benjamin W. Gung,* Xiaowen Xue and Zou Yan, “Enthalpy (H) and Entropy (S) for ∏-Stacking Interactions in Near-Sandwich Configurations: Relative Importance of Electrostatic, Dispersive, and Charge-Transfer Effects”, J. Org. Chem. 2007, 72, 2469.
2. Benjamin W. Gung,* Mehul Patel and Xiaowen Xue, “A Threshold for Charge-Transfer Effects in Aromatic Interactions? Quantitative Study of π-Stacking Interactions ”, J. Org. Chem. 2005, 70, 10532.
3. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “Off Center Oxygen-Arene Interactions in Solution: A Quantitative Study”, J. Org. Chem. 2005, 70, 7232.
4. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “The Strength of Parallel-Displaced Arene-Arene Interactions in Chloroform”, J. Org. Chem. 2005, 70, 3641.
5. Benjamin W. Gung,* Xiaowen Xue, Nina Knatz, and James A. Marshall, “Addition of chiral allenylzinc reagent to acetaldehyde: diastereotopic cyclic transition states with a tetrahedral zinc atom located by ab initio and density functional theory”, Organometallics 2003, 22, 3158. 医学全.在.线网站www.med126.com
6. Benjamin W. Gung,* Xiaowen Xue, and William R. Roush, “The origin of diastereofacial control in allyboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen”, J. Am. Chem. Soc. 2002, 124, 10692.
7. Benjamin W. Gung* and Xiaowen Xue, “Asymmetric transition states of allylation reaction: an ab initio molecular orbital study”, Tetrahedron: Asymmetry 2001, 12, 2955.

Resume
Xiaowen Xue,PhD, associate professor of Medicinal Chemistry , China Pharmaceutical University. Xiaowen Xue graduated from Nanjing College of Pharmacy with a BS in 1986 and worked as a teacher in the same college until he moved to USA to pursue his PhD in 2000. Xiaowen Xue obtained his PhD majoring at organic chemistry from Miami University in 2005, under the guidance of Prof Ben Gung. He then did his postdoctoral research at Miami for one year and returned to China Pharmaceutical University in 2006, where he holds the associate professorship. He is the member of American Chemical Society.  During his American career, Xiaowen Xue coauthored seven peer-reviewed publications at top chemistry journals such as the Journal of American Chemical Society and the Journal of Organic Chemistry.

Research Interests
The research on anticancer drugs; studies on weak noncovalent interactions; and the origins of some asymmetrical reactions.

References
1. Benjamin W. Gung,* Xiaowen Xue and Zou Yan, “Enthalpy (H) and Entropy (S) for ∏-Stacking Interactions in Near-Sandwich Configurations: Relative Importance of Electrostatic, Dispersive, and Charge-Transfer Effects”, J. Org. Chem. 2007, 72, 2469.
2. Benjamin W. Gung,* Mehul Patel and Xiaowen Xue, “A Threshold for Charge-Transfer Effects in Aromatic Interactions? Quantitative Study of π-Stacking Interactions ”, J. Org. Chem. 2005, 70, 10532.
3. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “Off Center Oxygen-Arene Interactions in Solution: A Quantitative Study”, J. Org. Chem. 2005, 70, 7232.
4. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “The Strength of Parallel-Displaced Arene-Arene Interactions in Chloroform”, J. Org. Chem. 2005, 70, 3641.
5. Benjamin W. Gung,* Xiaowen Xue, Nina Knatz, and James A. Marshall, “Addition of chiral allenylzinc reagent to acetaldehyde: diastereotopic cyclic transition states with a tetrahedral zinc atom located by ab initio and density functional theory”, Organometallics 2003, 22, 3158.
6. Benjamin W. Gung,* Xiaowen Xue, and William R. Roush, “The origin of diastereofacial control in allyboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen”, J. Am. Chem. Soc. 2002, 124, 10692.
7. Benjamin W. Gung* and Xiaowen Xue, “Asymmetric transition states of allylation reaction: an ab initio molecular orbital study”, Tetrahedron: Asymmetry 2001, 12, 2955

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