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医学论文范文:徐州矿区亚临床甲状腺疾病的流行特征及分析
【摘要】 目的 了解徐州矿区人群亚临床甲状腺疾病的患病率及流行特征。方法 应用分层随机整群抽样方法调查徐州矿区常住(>5年)成年居民共468人，采用问卷调查、体格检查、甲状腺B超检查和功能检测方法采集数据。结果 样本总人群、男性及女性亚临床甲状腺疾病的粗患病率分别为52.14%、37.01%和57.77%，甲状腺结节、亚临床甲状腺功能亢进症和亚临床甲状腺功能减退症的粗患病率分别为25.00%、4.06%和23.08%，亚临床甲状腺疾病的患病率随年龄的增加呈现上升趋势。女性甲状腺结节和亚临床甲状腺功能减退症患病率明显高于男性(P<0.05)，而男性亚临床甲状腺功能亢进症患病率高于女性(P<0.01)。性别和年龄是亚临床甲状腺疾病发生的危险因素。结论 徐州矿区成年人群亚临床甲状腺疾病患病率较高，应重视对矿区人群亚临床甲状腺疾病的筛查、治疗和随访。
【关键词】 徐州矿区;甲状腺疾病;亚临床;患病率
The epidemiological characteristics and analysis of subclinical thyroid diseasesin Xuzhou coal mine areas
ZHANG Shugui, JIAO Liang, GONG Ying, CAI Keying, LU Meiqi
(Department of Endocrinology, The Secend Affiliated Hospital of Xuzhou Medical College,
Xuzhou, Jiangsu 221006, China)
Abstract: Objective To explore the incidence and prevalence characteristics of subclinical thyroid diseases in Xuzhou coal mine areas. Methods 468 permanent residents from the coal mine areas of Xuzhou, who had their residence for at least five years and were aged 20 or above, were survey by stratified sampling with questionnaire, physical examination, thyroid B ultrasonic examination and functional testing in data collection. Results The prevalence of subclinical thyroid diseases in sample population, males and females was 52.14%, 37.01% and 57.77% and had a tendency of increase with age. The prevalence of thyroid nodules, subclinical hyperthyroidism and subclinical hypothyroidism was 25.00%, 4.06% and 23.08%, respectively. The prevalence of thyroid nodules and subclinical hypothyroidism was higher in females than in males (P<0.05), while males had a higher prevalence of subclinical hyperthyroidism(P<0.01). Conclusion The high prevalence of subclinical of thyroid diseases in adults in Xuzhou coal mine areas requires timely screening, treatment and follow-ups医学 全在.线提供www.med126.com.
Key words: Xuzhou coal mine area; thyroid diseases; subclinical; prevalence
亚临床甲状腺疾病是指无或仅有轻微甲状腺疾病相关症状，通过实验室检查或影像学手段发现的甲状腺异常，包括甲状腺结节、亚临床甲状腺功能亢进和亚临床甲状腺功能减退等[1]。随着诊断技术的不断发展，亚临床甲状腺疾病的早期检出率也越来越高。国内已经开展多项关于亚临床甲状腺疾病的流行病学研究，而针对矿区等特殊区域人群的相关流行病学研究仍未得到重视。本研究对徐州地区的旗山矿、张双楼矿、三河尖矿及卧牛山矿人群进行流行病学调查，从而为徐州矿区进行亚临床甲状腺疾病的防治提供基础依据。
